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Posts Tagged ‘Antiaging’

Azfibrocel-T Reviewed by FDA for Wrinkle Reduction

Posted by Cosmetic Surgery Review on October 25, 2009

Today’s innovative treatments for wrinkle reduction include laser skin resurfacing treatments, facelift surgery and dermal fillers such as Restylane and Botox. However, cell therapy may be another option for men and women in the United States in the near future.

Fibrocell Sicence, Incorporated, a biotechnology company focused on developing regenerative fibroblast cells for aesthetic, medical and scientific application has announced that the U.S. Food and Drug Administration’s Cellular, Tissue and Gene Therapies Advisory Committee is reviewing azfibrocel-T, an autulogous cell therapy for the treatment of nasolabial fold wrinkles in adults.

The FDA is currently evaluating the treatment under the brand name, Laviv ™. The treatment works by using the patient’s own natural fibroblasts. The fibroblasts are extracted, multiplied and then re-injected into the skin as a personalized treatment, allowing for the formation of new cells and stronger connective tissue fibers. Over time, this results in a significant reduction of wrinkles and fine lines, and creates a healthier, more rejuvenated appearance. Fibrocell Science, Incorporated is planning to continue studes for additional aesthetic and therapeutic sues.

Fibrocell Sicence, Incorporated is the result of the reorganization of Isalogen, Incorporated, a company emerging from bankruptcy. Azfibrocel-T was the sole topic of discussion at the Cellular, Tissue and Gene Therapies Advisory Committee Meeting on October 9, 2009 in Maryland. In may 2009, the FDA accepted azfibrocel-T for the treatment of moderate to severe nasolabial fold wrinkles for full review. The target date for an FDA response under the Prescription Drug User Fee Act is January 4, 2010.

If Laviv ™ becomes available in 2010, the treatment will be joining the ranks of fat transfer procedures, laser skin resurfacing and other skin rejuvenation treatments. Laviv ™ would be made available at many plastic surgery centers and aesthetic centers around the United States.

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Dr. Perricone Introduces Anti-Aging Perfume

Posted by Cosmetic Surgery Review on June 15, 2009

perfume-synergyDr. Nicholas Perricone, one of the industry’s leading anti-aging specialists, has recently introduced a new fragrance that promises to improve memory and mental clarity, reduce stress and boost self-confidence. The Neuropeptide Synergy elixir is now available on the market for $5 a drop, or $250 for a 25 ml bottle. Smaller quantities priced at $75 are also available, and it’s the first of its kind to promise the effects of a youthful state of mind with just a sniff.

The ‘magic’ behind this elixir is the mix of fragrances that deliver pheromones to the brain, causing several changes in the mental state and improving overall well-being. It’s been deemed an ‘anti aging perrfume’ because it uses the power of neuropeptides to increase the level of pheromones circulating in the body. The product just needs to be dabbed on the wrists or the nape of the neck, and results can be experienced within a few minutes.

Dr. Perricone’s prescription and message for fighting the signs of aging is to reduce stress and strengthen the immune system in several different ways.

Dr. Perricone encourages everyone to eat a well-balanced diet that contains an abundance of fruits, vegetables and whole grains, and to take supplements such as Omega-3 fatty acids and a vitamin complex to maintain good health. He specializes in skin care and skin health, and sells several anti-aging skincare products over the counter.

The Neuropeptide Synergy elixir is the latest addition to the anti-aging lineup, and it is designed to reduce stress and eliminate unpleasant feelings or negative energy that can lead to anxiety, depression and excessive fatigue. It acts primarily as a stress relieving perfume that may help many people calm down naturally, thereby reducing excess stress on the immune system and protecting the cells.

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Testosterone Deemed Essential for Anti-Aging

Posted by Cosmetic Surgery Review on May 30, 2009

j0321088While anti-aging pills and supplements promise to help reduce the effects of the aging process and combat fatigue, memory loss and other health problems, there may be a better solution. Doctors have confirmed that testosterone, and not estrogen as previously assumed, is the real “vitality” hormone, and that many women in particular can benefit from testosterone hormone therapy.

Dr. Rebecca Glaser, a breast cancer surgeon in Dayton, Ohio and anti-aging specialist, recently reported that women feel better after their menstrual cycle when estrogen levels are at their lowest.  When estrogen levels are too high, most women experience breast pain, fluid retention and severe PMS symptoms.

Dr. Glaser turns to a study to support her theory that testosterone is the necessary hormone for those who want to combat the effects of aging. This study shows that women between the ages of 33 and 74 were able to improve several severe symptoms including anxiety, physical exhaustion, heart discomfort, sleep problems and memory loss simply by using a small ‘pellet’ implant of testosterone that was placed under the skin. Increased levels of testosterone can also decrease body fat, increase muscle mass, and prevent the growth of breast tissue that is often caused by estrogen.

This pellet provides a continuous delivery of testosterone, and keeps hormone levels in balance. The procedure itself is relatively painless, and the woman cannot feel the pellet once it is inserted.

Some women may also benefit from making some dietary changes. Certain foods can increase testosterone levels naturally; these include bananas, raw oysters, cheese, brown rice, eggs, asparagus, and salmon.

Dr. Glaser points out that hormone therapy isn’t just designed for women who are going through menopause, and that many women can benefit from testosterone therapy. Testosterone pellet implants may be the missing link for many women struggling with sexual problems, exhaustion, joint pain and other health problems associated with aging.

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Anti-Aging Skincare Line Made with Replica Snake Venom Challenges Botox

Posted by Cosmetic Surgery Review on May 26, 2009

n_ject_image_lInstead of heading to the doctor’s office for a Botox fix or other dermal filler treatment that can zap away wrinkles, many people resort to skincare products made with natural ingredients such as hyaluronic acid, alpha lipoic acid and collagen extracts, to plump up the skin and reduce the appearance of wrinkles.

A new product made with replica snake venom has recently entered the market, and is one of the first skin-care lines in the world that promises to freeze fine lines and wrinkles by reducing muscle contractions under the skin.

This is essentially what dermal fillers such as Botox and Dysport are designed to do, but this skincare line does not require injecting compounds into the skin tissues. The product is instead applied directly onto the top of the skin and absorbed through the pores.

The product was developed by Brynja McGrady and Deborah Flattery, and is called Miracle Hydrate. It contains the patented Innovenom compounds, that are a replica of snake venom of the exotic temple viper. This synthetic viper venom was duplicated from the Malaysian Temple Viper’s venom, and is marketed as the newest Generation 6 peptide. The treatment has been named ‘Best Botox Alternative’ in Switzerland, and is available in five different formulations that combat various effects of aging.

Miracle Hydrate contains several anti-aging ingredients including hyaluronic acid, a natural skin-tightening and moisturizing agent, kombuchka, and the free radical fighter hydrolyzed algin. The proprietary treatments are a mixture of serums and moisturizers that are designed to improve the texture, tone and clarity of the skin, while reducing or eliminating the signs of wrinkles.

Miracle Hydrate products are currently available online, and retail for $40 to $120 per bottle, depending on the serum or moisturizer. The N ject Line Elimination Serum is priced at $120, and is the revolutionary product that promises to freeze the skin, slow down the aging process, and eliminate lines and wrinkles with the proprietary neuropeptide blend.

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Antioxidants in Certain Foods May Reduce Wrinkles

Posted by Cosmetic Surgery Review on May 20, 2009

j0436433Researchers at the Hallym University in the Republic of Korea recently reported a positive connection between the antioxidant ellagic acid and collagen preservation.

The studies conducted near the end of April 2009 indicate that several fruits and vegetables that contain high concentrations of ellagic acid can reduce the risk of sun damage and destruction to the skin cells, thereby offsetting wrinkles.

According to an article by, ellagic acid works by protecting the skin against UV damage, and reducing the effects of inflammation and destruction of the collagen molecules and enzymes under the skin’s surface. Topical application, not consumption of ellagic acid, may effectively help reduce wrinkle formation and help the skin become thicker and more resilient. (Source:

Ellagic acid has also been linked to a reduction in the inflammatory response on aging skin, which means that the rate of photo-aging could be slowed down significantly with regular topical application of the acid. The compound is readily available in raspberries, cranberries and pomegranates, and even some nuts and vegetables.

The tests were conducted on hairless mice, a breed that is often used for dermatology and anti-aging studies. The mice were first exposed to UV rays three times a week so they developed a mild sunburn. This damaged skin was then tested with applications of the ellagic acid, and researchers say the acid was especially effective for increasing the thickness of the skin, and preventing collagen breakdown. Researchers confirmed that wrinkle formation was reduced significantly because of the ellagic acid, and that ellagic acid may be effective at reducing the risk of collagen destruction and inflammation after sun damage.

Cosmetic companies and anti-aging specialists may soon be able to take advantage of the properties in natural ingredients such as strawberries and pomegranate to combat the signs of aging.

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Trilexon Approved for Cosmetic Market

Posted by Cosmetic Surgery Review on April 29, 2009

CB005062If you’ve been prescribed a topical drug or ointment to take care of burns, scars and other skin conditions, your doctor may have used laser devices and other equipment to improve the rate of absorption in the skin.

A new delivery system has become available, and was recently approved for use in the cosmetic market. Trilexon skincare products help to increase the absorption rate of various skincare products so that the skin can react almost immediately to the preparation.

Trilexon is a registered trademark of Greyson International. In a recent press release, Harvey Tauman, CEO of Greyson International explains that “This is a very important step for us as we move forward from our developmental and research stage, into the marketing and sales stage for Greyson’s products and applications.” The company makes several health and beauty products, and the Trilexon system is one of the most innovative products to date. The company makes its own line of cleansers, anti-wrinkle creams, alcohol-free skin toners and collagen creams, as well as beauty ‘kits’ and skincare regimens specifically for anti-aging customers. The Trilexon system may help to improve the effects of these products.

Many people are required to wait several weeks, and even months before they see results with standard topical applications. Even medical-grade products require several uses before any effects can be achieved, and the skin needs to undergo its usual cell turnover and renewal process before the skin really starts to ‘take’ the ointment or product. Trilexon can help to speed up the absorption rates of standard products, thereby improving the overall cell turnover and renewal process.

The Trilexon system can be used with virtually any topical application or topical drug, and may soon become available at medical spas, dermatology offices, cosmetic surgery centers, and anti-aging/wellness centers around the country.

Source: Greyson International Press Release

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Demand for Anti-Aging Products Stays Strong During Recession

Posted by Cosmetic Surgery Review on April 16, 2009

CB107484Even though people are cutting back on personal luxuries and extra expenses during the recession, few women are willing to part with their beauty regimen.

According to a recent market forecast by Mintel, a market research agency, women are actually spending more on cosmetics and over-the-counter anti aging treatments during these tough economic times.

Cosmetic sales increased significantly these past few years as the economy tumbled; Mintel predicts a 10% increase in the next five years, and Mintel says this is largely because women have an emotional tie to their appearance so ‘feel good luxuries’ such as makeup, beauty and skincare products are a necessity when things become stressful.

Anti-aging products, sun care products and skincare treatments are turning into ‘non-negotiable’ purchases during the recession, and the trend is on the rise. Mintel forecasts a 20% growth in anti-aging skincare product sales over the next five years, and a 36% growth in demand for sun care products over the same period. While these statistics are slightly lower than forecasted a few years ago, demand for these items will still remain strong despite the economic upheaval.

In addition to makeup and skincare, cosmetic surgeons in the United States and in Europe are experiencing a significant increase in demand for Botox, Restylane and other non-surgical procedures. Since most people aren’t prepared to spend thousands of dollars for facelift surgery, they are finding other ways to improve their looks. More affordably-priced procedures such as Botox (average $400 per injection), and Velashape or Velasmooth ($300 per treatment) can help get rid of wrinkles and reduce the appearance of cellulite. These procedures are readily available at medical spas and aesthetic surgery centers around the country, and some clinics are extending a discount for clients who purchase a package or series of treatments.

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Initial Aquamid Wrinkle Filler Trials Proving to Be a Success

Posted by Cosmetic Surgery Review on March 16, 2009

aquamidInjectable fillers continue to be an affordable and safe anti-aging treatment for many people looking for a quick-fix for treating wrinkles, enhancing the lips or balancing out the nose. While dermal fillers such as Botox, Restylane and Juvederm are among the most sought-after injectables in today’s non-surgical market, researchers are testing many other compounds so that patients have even more options in the near future.

Aquamid wrinkle fillers have been undergoing trials and testing for several years, and are finally appearing in select cosmetic surgery centers and medical spas around the world. Dr. Rhonda Narins, a dermatologist in New York recently reported on the results of her participation in a study of Aquamid. The 30 patients in her trial project did not experience any problems with the injectable, and did enjoy immediate results. (Source:

Aquamid is a transparent injectable that can be used for lip augmentation, smoothing out nasolabial folds, getting rid of deep wrinkles, and even as part of a rhinoplasty procedure. The injectable is physically and chemically stable, and very soft and malleable. Individuals who are allergic to some of other compounds present in today’s leading dermal fillers may be good candidates for this injectable that promises easy administration and no allergic reactions.

In addition to filling out lines and wrinkles, Aquamid can be used to contour the face; surgeons have used it to sculpt high cheekbones, enhance the lips and create more contours around the face for a more sculpted, youthful appearance. Results are immediate, and the filler does not degrade over time; according to the company website, Aquamid provides aesthetic satisfaction for years after the first treatment; It restores facial volume for the long-term, providing natural, lasting results.

According to Contura International, the company that makes Aquamid, the injectable has been used in over 40 countries. It is not yet available in the United States, and may still need to undergo thorough FDA review and trials before reaching the U.S. cosmetic surgery market.

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New Wave of Beauty Innovations Presented at AAAS Annual Meeting

Posted by Cosmetic Surgery Review on February 28, 2009

42-16020607The AAAS Annual Meeting took place in Chicago from February 12-16, 2009 to provide some insights on the latest beauty innovations on the horizon. Scientists from P&G Beauty & Grooming presented research and product demonstrations for several advanced beauty and grooming products, giving show attendees a preview of some of the latest technologies and products for anti aging, skin rejuvenation and facial enhancement.

According to a press release about the event from Medical News Today, top topics included: color science, genomics of skin aging, hair science and grooming science.

The color science presentation provided information on how skin defects such as under eye circles, age spots and skin discoloration vary across different populations and regions, and how this knowledge can be used to create natural-looking cosmetic foundation. Light absorption and light scattering principles are some of the key factors involved when using cosmetic foundation to hide flaws and create a natural appearance, and researchers are focusing on ways to optimize compounds in foundation so that it can provide the most flawless finish.

The genomics presentation offered insights on how gene expression patterns can change when exposed to the sun, and how this effects the aging process. UV light and photo-aging are of tremendous concern to those who live in sunny environments, and the next generation of products may include age reversal and intensive photofacial treatments.

The hair science presentation covered topics about how hair becomes damaged, and what products can help to restore or strengthen the hair fibers. Coloring, bleaching and excessive sun exposure are some of the most damaging factors of all hair types, and researchers are working on liquid crystal technology solutions that may be able to prevent or reverse some of this damage.

Finally, the grooming science presentation took a close look at the value of five-blade razors, a concept that has taken almost 90 years to perfect. Multi-blade razors may be able to produce a very close shave and leave the skin looking flawless and smooth. This could set a new standard or the grooming industry, and is currently under development by P&G.

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Free Radicals May Not Be Linked to Aging Process

Posted by Cosmetic Surgery Review on January 1, 2009

agingHealth and wellness experts have long claimed that free radicals are the ‘aging accelerators’ that can lead to many common diseases and skin conditions associated with the aging process.

However, researchers at the Institute of Healthy Aging University College in the U.K. have recently revealed their findings about free radicals and claim that antioxidants do not have a significant impact on degenerating cells.

The results of the research were disclosed in the November 2008 issue of the Genes & Development publication, and the conclusion states that oxidative damage is not necessarily linked to the ageing process.  The tests were performed on nematode worms to find out which processes were involved in removing free radicals from the body.  The worm’s ability to flush away toxins and ‘superoxides’ did not have any effect on the worm’s lifespan, which may mean that the process of reducing oxidative damage may not be as harmful as was once thought.

Many skincare specialists and anti-aging physicians have claimed that products and treatments that contain antioxidants can help slow down the aging process and even eliminate the signs of aging.

Cosmetics and skincare products are often marketed as having ‘anti-aging’ properties because of the high levels of antixodants on the ingredients list.  However, this study may be a basis for disproving these claims; the aging process may not be linked to free radicals, but may and products that have antioxdants may be relatively ineffective.

In most cases, the signs of aging are a result of genetics and lifestyle habits.  Healthy skin management may reduce the effects of aging by ensuring optimal collagen production and protecting pores and skin cells.  Genes are largely responsible for the development of wrinkles and the extent of skin damage with age.  An anti-aging specialist can determine the extent of damage and recommend treatments that may help slow down or reverse some of the signs of skin damage; using products with antioxidants may not be a viable strategy.

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