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Archive for the ‘wrinkle treatments’ Category

Physicists Find Clues to the Evolution of Wrinkles

Posted by Cosmetic Surgery Review on July 24, 2010

Researchers at the University of Massachusetts, Amherst have been studying the evolution of wrinkles in a recent dermatological study, and have published several papers in the current issue of Physical Review Letters about their findings. Scientists are attempting to understand the formation of wrinkles in biological tissue, and looked at how wrinkles in a sheet adapt to an edge that tends to be flat.

In a related study, researchers looked at the transition from soft wrinkles to sharper folds, and proved that folds in the tissue, like the edges of a neatly made bed, strain the sheet and help to smooth out wrinkles.

Physicists are looking primarily at the superficial causes and effects of wrinkle formation, but for many years, researchers have also taken a close look at the effects of toxins in the environment, the role of antioxidants in the diet, and the effects of various skin care products in the formation of wrinkles. Many experts suggest that wrinkle formation is largely the result of genetics and lifestyle factors, such as smoking, diet and exercise.  Wrinkle treatments such as laser skin resurfacing and skin rejuvenation procedures can help to reverse many of the signs of aging.

Individuals who spend a lot of time in the sun do increase their risk of getting wrinkles because UV rays can break down collagen in the skin which makes the skin weaker. Overexposure to the sun can cause premature wrinkles around the eyes, mouth and nose, and also increase the chances of skin cancer.

Some experts suggest that a balanced diet that contains a high concentration of antioxidant-rich foods can also ward off wrinkles and improve the skin’s appearance. Foods that are high in antioxidants may help to increase the firmness of the skin and increase skin elasticity. Some foods that are high in antioxidants and also contain iron can help bring oxygen to the skin and prevent premature aging.

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Hyperoxia May Slow Down Formation of Wrinkles

Posted by Cosmetic Surgery Review on July 16, 2010

A recent study published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology shows that oxygen infusions to the skin may help reduce the formation of wrinkles and also reduce the risk of tissue damage from UVB rays. Many people who exhibit the visible signs of aging, including wrinkles and lines around the eyes, nose and mouth, and a thickening of the outer layer of the skin, have been overexposed to UVB rays.

In this study, mice who were exposed to UVB radiation and then placed in an oxygen chamber showed fewer signs of tissue damage and wrinkles than those who were exposed to UVB radiation without time in the oxygen chamber. The researchers assigned 24 hairless mice into three groups for testing, and those that were exposed to UVB radiation were placed under a special fluorescent lamp three times per week, for five weeks. Some were then placed in an oxygen chamber or two hours after each session under the lamp.

Researchers found that all of the mice exposed to UVB rays did develop wrinkles over the five week period, but those who did not spend time in the oxygen chamber showed more pronounced wrinkles and an increase in epidermal thickness. Researchers note that additional studies are required to form any conclusions, but in the meantime, it is still a good idea to avoid excessive UVB exposure by wearing sunscreen.

While many people who spend a lot of time in the sun do develop wrinkles more readily, there are several ways to protect the skin, and even reverse the wrinkle formation process. Dermatologists recommend wearing sunscreen and staying out of direct sunlight or tanning bed. Skin tightening treatments such as Thermage or Titan, and skin rejuvenation procedures such as Fraxel laser skin resurfacing can effectively get rid of wrinkles for good.

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Research Reveals How Skin Fillers Stimulate Collagen Production

Posted by Cosmetic Surgery Review on March 15, 2010

Demand for minimally invasive procedures including Botox, Restylane and other injectable fillers continues to be strong in the United States and abroad, even more so in the wake of the economic recession.

Soft tissue injectables are not only effective for getting rid of wrinkles, reducing the appearance of fine lines and plumping up the skin, but can also help to improve the appearance of aging and sun-damaged skin by making the skin appear more resilient and smooth.

At this year’s American Academy of Dermatology Meeting, dermatologist Dana L. Sachs, MD, FAAD, associate professor in the department of dermatology at the University of Michigan in Ann Arbor, Michigan presented findings of a study that demonstrated how certain types of hyaluronic acid dermal fillers can stimulate collagen production and help to repair the skin. These may be some of the known side effects of certain fillers, and can help some patients achieve a more youthful look after a single treatment.

Structural damage to the skin is one of the most significant effects of the aging process, and the breakdown of collagen and elastin only increases at a steady rate as the individual ages. The common effects of aging include fine lines, skin laxity and pigmentation. Advanced stages of photoaging result in coarse wrinkles, redness and discoloration of sun-exposed skin. Some types of tissue fillers may be effective at changing the skin’s structure, reducing the effects of fragmentation and helping the tissues regenerate higher levels of collagen which creates a smooth and healthy appearance.

Dr. Sachs reports, “from a clinical standpoint, dermatologists know that soft tissue fillers work by restoring volume loss and smoothing wrinkles in aging and sun-damaged skin…the biochemical study of cross-linked hyaluronic acid conducted by researchers set out to explain what takes place at the molecular level to account for the observed clinical improvements.” (Source: Medical News Today)

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Coolaser Offers New Option for Treating Crows Feet

Posted by Cosmetic Surgery Review on January 25, 2010

The small wrinkles that develop around the edges of the eyes and around the lash line are among the telltale signs of aging, but there are several cosmetic procedures that can help to reduce the appearance of these lines – also known as crows feet – or eliminate them altogether.

Skin tightening treatments and Botox injections can provide temporary wrinkle relief, but an innovative laser that works by promoting collagen regrowth may also offer some benefits.

The Coolaser device is desgiend to deliver laser energy deep into the top layer of the skin and causes the skin tissues to contract. In this procedure, the entire surface of the skin is first cooled using a special device, and then a series of light pulses are emitted onto the skin’s surface. The skin cells absorb the light energy to completely vaporize the cells. As the physician passes this light over the skin, small amounts of tissue are removed. Since this is perceived as damage to the skin, collagen production increases. This tightening effect helps to strengthen the skin and restores elasticity.

The Coolaser device is currently performed at the office of Dr. Simon Ourian, the Medical Director of Epione Medical Corporation of Los Angeles, and so far, has delivered very promising results.

In addition to treating wrinkles, the Coolaser is designed to remove superficial blemishes and can also even out an uneven skin tone. The treatment takes between 10 to 15 minutes, and the depth of penetration can be adjusted according to the person’s skin type.

Patients can turn to this innovative laser technology to eliminate wrinkles, but are also advised to take care of their skin by using Retin-A topical skin creams (available only by prescription), or by undergoing a skin tightening treatment that helps to tighten all of the skin around the face and neck area.

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Woman Files Lawsuit After Getting Evolence Injections

Posted by Cosmetic Surgery Review on November 30, 2009

Mara Micevic of Oakville received Evolence injections in January 2007 from a local laser and spa clinic after the center promised she could improve her looks and achieve a more youthful appearance. Ms. Micevic states that “she didn’t think twice” about getting the injections because she had known many women who had gone to these types of clinics and had been able to improve their appearance.

However, Micevic reports that immediately after Evolence was injected into her lips, she could feel a set of “small balls” under her skin and was assured that they would disappear. Eight months later, she developed a bump under her top lip that began to ooze pus and blood. Soon after, her whole face was swollen and she got infections over her entire face.

Ms. Micevic contacted the manufacturer in 2008, she found out that Evolence was not indicated for use in the lips at all.  However, the filler had been marketed as an all-natural filler for lip augmentation in the United States and in Canada, and was made available at several medical spas and cosmetic surgery centers around the country.

Evolence is among the newest dermal fillers on the market, an injectable that promises to fill out fine lines and wrinkles instantly and produces natural-looking results. It costs approximately $500 per injection, and according to the American Society of Plastic Surgeons, Americans are spending approximately $800 million per year on injectables.

Some injectables, such as collagen fillers, do have a high risk of allergies and doctors may need to do a test before administering the entire injectable.

For Micevic, the side effects were enough to prompt a lawsuit against Johnson & Johnson and related companies who are failing to warn the public about the risk of injury, scarring, infection and disfigurement from using Evolence.  Two other women in Richmond, B.C. have also launched a notice to sue over Evolence in December 2008.

On November 3, 2009, Johnson & Johnson announced that it would discontinue the manufacture and marketing of Evolence products.

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Dermaxin Wrinkle Cream Promises Results Similar to Injectables

Posted by Cosmetic Surgery Review on November 29, 2009

Millions of men and women opt for dermal fillers and injectables such as Zyderm, Zyplast, Botox, Restylane and Juvederm to fill out lines and wrinkles, smooth out sagging skin and enhance their appearance.

The popularity of the ‘liquid facelift’ has encouraged many surgeons and aesthetic surgery professionals to sell more products that offer a quick fix for lines and wrinkles, and demand for brans including CosmoDerm, Dermalogen and Dysport has increased significantly over the past ten years.

Now, a wrinkle cream that has been deemed the world’s best topical collagen delivery system claims to offer results similar to injectables.

Dermaxin is the world’s leading anti-wrinkle cream, an all-natural collagen cream that penetrates deep into the skin within the first ten minutes after application. According to studies conducted by Dermaxin researchers, most people saw an overall reduction of wrinkles within the first 4 to 12 weeks of daily use (up to a 44% difference).

Since most injections cost between $500 to $1000 per series, Dermaxin offers a more affordable solution for getting rid of wrinkles, and does not require touchup treatments and appointments at a doctor’s office. Some people who are allergic to the toxic compounds in many injectables or those who experience burning and irritation at the injection site may be good candidates for a topical wrinkle treatment instead.

According to Dermaix spokesperson Teresa Richards, “Dermaxin uses is the most powerful delivery system in the world – Hyaluronic Acid – to penetrate the folds of the ski and supply collagen to the deep dermal layers…the same instantaneous wrinkle-busting and smoothing effect found with injections is also achieved –within the first ten minutes of using the product – thanks to the power of Acetyl Hexapeptide08, a proven facial-relaxing compound and wrinkle remover that provides results similar to those of Botox, but without any of the associated risks.” (Source: Dermaxin Press Release)

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American Society of Dermatologic Surgery Investigates Aquamid Fillers

Posted by Cosmetic Surgery Review on October 27, 2009

teen faceThe results of a recent study investigating the injectable Aquamid were revealed at The American Society of Dermatologic Surgery (ASDS) 2009 meeting.

Aquamid is an injectable filler designed to treat fine lines and wrinkles, and is made with 2.5% polyacrylamide hydrogel and, according to the results of the study, is as well tolerated as hyaluronic acid fillers such as Restylane and Juvederm.

Rhoda Narins, MD, Clinical Professor of Dermatology of the New York University School of Medicine in New York City and Director of the Dermatology Surgery and Laser Center of New York reports that, “our results demonstrate that polyacrylamide hydrogel shows strong potential as a permanent soft tissue filler.” The ingredients in Aquamid are non-biodegradable, which means this particular filler cannot migrate. The compound is also expected to last longer than traditional hyaluronic fillers, which may be a cost benefit to consumers.

Aquamid is marketed as a soft volume filler to enhance facial contours, fill out nasolabial folds, smooth out wrinkles and folds in the cheeks and lips, and can also be used to reshape the nose. The filler boasts natural-looking results and lasting satisfaction. In long-term clinical trials, physicians judged the aesthetic results at one, two and four year intervals, and found that results were still good or very good for more than 90% of patients at each interval.

Data after five years shows that patients were either very satisfied or satisfied with results during the follow-up session, and the filler produced similar aesthetic results. The filler is designed to completely integrate with the body’s tissues, which means there is no risk of an allergic reaction to the micro-particles present in the compound. Aquamid is also not linked to tissue hardening or fibrosis.

Efficacy of Aquamid was maintained through the 12-month post follow up treatment for the filler, and showed a significant improvement in results in treatment groups.

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Azzalure Deemed ‘Baby Botox’ for Subtle Lines

Posted by Cosmetic Surgery Review on August 23, 2009

42-15653301While many men and women run to the plastic surgeon’s office to get a much-needed Botox injection upon the arrival of a few wrinkles on the forehead, others are choosing a milder version for a more natural look.

Botox injections can deliver an ‘instant facelift’ and get rid of deep expression lines and furrows in one simple treatment. Researchers report that Botox can also improve your mood, give you more self-confidence and increase your chances of landing that dream job.

However, Botox injections can also create an artificial, ‘surprised’ look that makes it obvious that cosmetic work has been done. While some celebrities and other Botox addicts prefer a super-smooth appearance, others would rather achieve more natural-looking results.

Many doctors in the United States and the United Kingdom are giving their patients an injectable called Azzalure as an alternative to Botox. Azzalure is designed to soften up lighter lines and wrinkles around the face, and may be more appropriate for men and women in their late 20s and 30s who only need a mild treatment.

Azzalure has been deemed the ‘baby Botox’ of our generation, and is designed to enhance existing features, not just ‘fix’ fine lines and wrinkles. The procedure involves a small series of pinpricks (rather than a single injection), and the filler is injected into specific muscles around the forehead to create a smooth, natural appearance.

Results last approximately the same as a Botox treatment, and prices vary depending on the doctor and amount needed. According to Dr. Aamer Khan of the Harley Street Medical Skin Clinic in London, “[Using Azzalure] is a balancing act…but administered in tiny quantities with an aesthetic eye the results can be stunning.” (Source: The UK Telegraph)

Azzalure has been approved in the UK for aesthetic use and is manufactured by Ipsen, the same company that has introduced the injectable Dysport to the U.S. market.

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New Drug May Help Slow Down Aging Process

Posted by Cosmetic Surgery Review on July 21, 2009

CB008328Many and women head to the plastic surgeon’s office to get rid of wrinkles, tighten up loose skin and defy the aging process, but there may soon be another option.

According to results of a research study published by Randy Strong, PhD of the Aging Interventions Testing Center in San Antonio, a drug that was found in the soil of Easter Island in the South Pacific may be effective at slowing down the aging process.

Rapamycin has extended the life expectancy of middle-aged mice used to conduct the research by as much as 38%, and researchers believe that the drug may not only slow down the development of wrinkles and other signs of aging, but can also lower the risk of heart disease and certain types of cancer in humans. Rapamycin may be effective at postponing death from cancer, and slowing down several ageing processes that are linked to cell metabolism. According to a recent article in WebMD.com, rapamycin has immunosuppressant properties and is also being studied as a potential anticancer drug. Still, experts say it is too soon to believe that  this drug can and will have a positive effect on humans.

The Aging Interventions Testing Center is funded by the National Institute of Aging, and the drug is the first to have shown a significant increase in life span in both male and female mice. The drug was delivered in a time-release formula that allowed for better absorption in the bloodstream. In the future, the drug may be combined with other drugs and medications in order to achieve desired results.

While more research and tests are required to determine if similar effects can be achieved in humans, researchers can now count on data that shows new molecular pathways for other drugs that may be effective in improving overall health and slowing down the ageing process.

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Prevention Magazine Encourages Women in their 40s to Embrace Retinoids

Posted by Cosmetic Surgery Review on July 19, 2009

j0337407Take a trip to the cosmetics counter at any department store and you will be bombarded with the latest anti-aging products, serums, creams and makeup that promise to zap wrinkles and improve your looks.

For women in their 40s, the quest for a more youthful look is often high on the priority list, and there are now hundreds of products on the market designed specifically for this demographic segment. Some experts believe that maintaining a youthful appearance could be as simple as applying retinoid-based creams and serums to the skin.

Dr. Ranella Hirsch, president of the American Society of Cosmetic Dermatology and Aesthetic Surgery and a cosmetic dermatologist in Cambridge, Massachusetts recently interviewed with Prevention magazine to discuss the effects of aging on women in their 40s, 50s and 60s, and to provide some insights on what women can do about wrinkles, fine lines and other skin issues as they age. “Embrace retinoids” was the directive for women in their 40s that want to improve the texture and tone of their skin, and reduce the risk of developing future wrinkles.

According to the article in Prevention magazine, “retinoids rev up sluggish cell turnover, so skin becomes smoother and more radiant, and dark spots fade.” (Source: msnbc.com)

Retinoid creams are available over the counter, and many require daily or nightly application for a period of 8 to 12 weeks in order to achieve results. Drugstore products may also be more effective for sensitive skin and for those who have not undergone any cosmetic surgery or non-invasive procedures, because medical-grade products are often harsh on the skin.

Many medical spas and aesthetic surgery centers also offer retinoid-based treatments as part of a facial or anti-aging package. These incorporate retinoid creams and serums into the treatment so that the skin can absorb the compounds more readily. In these cases, results can be achieved within a few days after the treatment.

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