International Study Links Genetics to Melanoma
Posted by Cosmetic Surgery Review on July 14, 2009
Melanoma, the deadliest form of skin cancer, can be the result of overexposure to UV rays from the sun or tanning booths. Until recently, dermatologists and medical professionals strongly linked the risk of melanoma to excessive sun exposure and sun sensitivity, and a genetic disposition to developing skin cancer.
Now, recent research confirms that genetics does play an important role in the development of melanoma, and may explain why people with the most moles on their skin have the highest risk of developing melanoma.
According to a study led by Professors Julia Newton Bishop and Tim Bishop of the Melanoma Genetics Consortium (GenoMEL) at the University of Leeds in the UK, people with genes that gave them red hair and freckles, and those who develop moles very easily, are at an increased risk of melanoma. The study examined the genetic makeup of over 10,000 people and compared the results with those who have developed the disease, and those who have not. They found several genetic commonalities between the participants of the study, and those who had developed melanoma. Those who tend to have burn easily, have sensitive skin, and tend to get freckles are increasingly at risk for developing skin cancer.
While the results of the study confirmed what many researchers already knew, the link between certain genes and the risk of melanoma had not been researched in-depth or reported on until this time. Results of the study were published in the online issue of Nature Genetics, and point to the actual genes associated with the increased risk of melanoma and skin cancer.
Staying out of direct sunlight is only one way to reduce the risk of developing skin cancer, as it is just as important for people to wear appropriate sun protection when they are outdoors or will be exposed to indirect sunlight. Melanoma is fatal, and those who are at a higher risk of developing this disease must take extra measures to protect themselves against excess sun exposure.